The HUB is “centering margins” to accelerate biomaterials technology development and translation. We are applying a powerful framework developed by thought leader Bell Hooks, which defined any group as having a center and margin; The most innovative, impactful, equitable, and inclusive work happens when concepts and individuals at the margins are brought to the center. To apply this framework, the HUB identifies powerful emerging technologies currently at the margins of our field, such as computation and AI, active materials, synthetic proteins, and more, and brings these technologies to the center of the biomaterials field. We also centralize critical resources that were previously marginalized. Finally, we prioritize funding of ideas, topics, and lenses through which to look at problems that have been historically overlooked. We envision that this approach of centering margins will transform the culture and science of biomaterials to catapult our field forward.